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Ancestral L-amino acid oxidases for deracemization and stereoinversion of amino acids
L-amino acid oxidases (LAAOs) can be applied to convert racemic amino acids to D-isomers, which are potential precursors of pharmaceuticals. However, this application is hampered by the lack of available stable and structure-determined LAAOs. In this study, we attempt to address this limitation by u...
Autores principales: | Nakano, Shogo, Kozuka, Kohei, Minamino, Yuki, Karasuda, Hiroka, Hasebe, Fumihito, Ito, Sohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814856/ https://www.ncbi.nlm.nih.gov/pubmed/36703379 http://dx.doi.org/10.1038/s42004-020-00432-8 |
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