Simultaneous sensing and imaging of individual biomolecular complexes enabled by modular DNA–protein coupling

Many proteins form dynamic complexes with DNA, RNA, and other proteins, which often involves protein conformational changes that are key to function. Yet, methods to probe these critical dynamics are scarce. Here we combine optical tweezers with fluorescence imaging to simultaneously monitor the con...

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Detalles Bibliográficos
Autores principales: Avellaneda, Mario J., Koers, Eline J., Minde, David P., Sunderlikova, Vanda, Tans, Sander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814868/
https://www.ncbi.nlm.nih.gov/pubmed/36703465
http://dx.doi.org/10.1038/s42004-020-0267-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814868/
https://www.ncbi.nlm.nih.gov/pubmed/36703465
http://dx.doi.org/10.1038/s42004-020-0267-4

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