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Biomimetic enantioselective synthesis of β,β-difluoro-α-amino acid derivatives

Although utilization of fluorine compounds has a long history, synthesis of chiral fluorinated amino acid derivatives with structural diversity and high stereoselectivity is still very appealing and challenging. Here, we report a biomimetic study of enantioselective [1,3]-proton shift of β,β-difluor...

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Detalles Bibliográficos
Autores principales: Peng, Qiupeng, Yan, Bingjia, Li, Fangyi, Lang, Ming, Zhang, Bei, Guo, Donghui, Bierer, Donald, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814941/
https://www.ncbi.nlm.nih.gov/pubmed/36697625
http://dx.doi.org/10.1038/s42004-021-00586-z