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Organocatalytic atroposelective heterocycloaddition to access axially chiral 2-arylquinolines

Axially chiral heterobiaryls play a vital role in asymmetric synthesis and drug discovery. However, there are few reports on the synthesis of atropisomeric heterobiaryls compared with axially chiral biaryls. Thus, the rapid enantioselective construction of optically active heterobiaryls and their an...

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Detalles Bibliográficos
Autores principales: Yang, Gongming, Sun, Shaofa, Li, Zhipeng, Liu, Yuhan, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814953/
https://www.ncbi.nlm.nih.gov/pubmed/36697620
http://dx.doi.org/10.1038/s42004-021-00580-5