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Organocatalytic atroposelective heterocycloaddition to access axially chiral 2-arylquinolines
Axially chiral heterobiaryls play a vital role in asymmetric synthesis and drug discovery. However, there are few reports on the synthesis of atropisomeric heterobiaryls compared with axially chiral biaryls. Thus, the rapid enantioselective construction of optically active heterobiaryls and their an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814953/ https://www.ncbi.nlm.nih.gov/pubmed/36697620 http://dx.doi.org/10.1038/s42004-021-00580-5 |