Synthesis of aryldifluoromethyl aryl ethers via nickel-catalyzed suzuki cross-coupling between aryloxydifluoromethyl bromides and boronic acids

As a unique organofluorine fragment, gem-difluoromethylated motifs have received widespread attention. Here, a convenient and efficient synthesis of aryldifluoromethyl aryl ethers (ArCF(2)OAr’) was established via Nickel-catalyzed aryloxydifluoromethylation with arylboronic acids. This approach feat...

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Detalles Bibliográficos
Autores principales: Lu, Heng, Xiao, Ruo-Xuan, Shi, Chang-Yun, Song, Zi-Lan, Lin, Hou-Wen, Zhang, Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814959/
https://www.ncbi.nlm.nih.gov/pubmed/36697792
http://dx.doi.org/10.1038/s42004-022-00694-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814959/
https://www.ncbi.nlm.nih.gov/pubmed/36697792
http://dx.doi.org/10.1038/s42004-022-00694-4

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