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Synthesis of aryldifluoromethyl aryl ethers via nickel-catalyzed suzuki cross-coupling between aryloxydifluoromethyl bromides and boronic acids
As a unique organofluorine fragment, gem-difluoromethylated motifs have received widespread attention. Here, a convenient and efficient synthesis of aryldifluoromethyl aryl ethers (ArCF(2)OAr’) was established via Nickel-catalyzed aryloxydifluoromethylation with arylboronic acids. This approach feat...
Autores principales: | Lu, Heng, Xiao, Ruo-Xuan, Shi, Chang-Yun, Song, Zi-Lan, Lin, Hou-Wen, Zhang, Ao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814959/ https://www.ncbi.nlm.nih.gov/pubmed/36697792 http://dx.doi.org/10.1038/s42004-022-00694-4 |
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