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s-ketamine enhances thalamocortical and corticocortical synaptic transmission in acute murine brain slices via increased AMPA-receptor-mediated pathways

Despite ongoing research efforts and routine clinical use, the neuronal mechanisms underlying the anesthesia-induced loss of consciousness are still under debate. Unlike most anesthetics, ketamine increases thalamic and cortical activity. Ketamine is considered to act via a NMDA-receptor antagonism-...

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Detalles Bibliográficos
Autores principales: Bieber, Matthias, Schwerin, Stefan, Kreuzer, Matthias, Klug, Claudia, Henzler, Marie, Schneider, Gerhard, Haseneder, Rainer, Kratzer, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814968/
https://www.ncbi.nlm.nih.gov/pubmed/36618009
http://dx.doi.org/10.3389/fnsys.2022.1044536