Genome-wide 5-hydroxymethylcytosine (5hmC) reassigned in Pten-depleted mESCs along neural differentiation

DNA methylation and hydroxymethylation have been implicated in the regulatory dynamics of gene expression in normal development and differentiation. 5-Hydroxymethylcytosine (5hmC), created by the ten-eleven translocation (TET) protein-catalyzed oxidation of 5-methylcytosine (5mC), is abundant in the...

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Detalles Bibliográficos
Autores principales: Wang, Zhangting, Miu, Kai-Kei, Chan, See-Wing, Ou, Fanghong, Wai-Nok Law, Patrick, Chan, Wai-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814970/
https://www.ncbi.nlm.nih.gov/pubmed/36619862
http://dx.doi.org/10.3389/fcell.2022.956604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814970/
https://www.ncbi.nlm.nih.gov/pubmed/36619862
http://dx.doi.org/10.3389/fcell.2022.956604

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