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Genome-wide 5-hydroxymethylcytosine (5hmC) reassigned in Pten-depleted mESCs along neural differentiation

DNA methylation and hydroxymethylation have been implicated in the regulatory dynamics of gene expression in normal development and differentiation. 5-Hydroxymethylcytosine (5hmC), created by the ten-eleven translocation (TET) protein-catalyzed oxidation of 5-methylcytosine (5mC), is abundant in the...

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Detalles Bibliográficos
Autores principales:	Wang, Zhangting, Miu, Kai-Kei, Chan, See-Wing, Ou, Fanghong, Wai-Nok Law, Patrick, Chan, Wai-Yee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9814970/ https://www.ncbi.nlm.nih.gov/pubmed/36619862 http://dx.doi.org/10.3389/fcell.2022.956604

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