Scaling‐down biopharmaceutical production processes via a single multi‐compartment bioreactor (SMCB)

Biopharmaceutical production processes often use mammalian cells in bioreactors larger than 10,000 L, where gradients of shear stress, substrate, dissolved oxygen and carbon dioxide, and pH are likely to occur. As former tissue cells, producer cell lines such as Chinese hamster ovary (CHO) cells sen...

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Detalles Bibliográficos
Autores principales: Gaugler, Lena, Mast, Yannic, Fitschen, Jürgen, Hofmann, Sebastian, Schlüter, Michael, Takors, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815078/
https://www.ncbi.nlm.nih.gov/pubmed/36619888
http://dx.doi.org/10.1002/elsc.202100161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815078/
https://www.ncbi.nlm.nih.gov/pubmed/36619888
http://dx.doi.org/10.1002/elsc.202100161

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