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T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint proteins

BACKGROUND: Galectin-9 is a member of the family of lectin proteins and crucially regulates human immune responses, particularly because of its ability to suppress the anticancer activities of T lymphocytes and natural killer cells. Recent evidence demonstrated that galectin-9 is highly expressed in...

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Detalles Bibliográficos
Autores principales: Schlichtner, Stephanie, Yasinska, Inna M, Lall, Gurprit S, Berger, Steffen M, Ruggiero, Sabrina, Cholewa, Dietmar, Aliu, Nijas, Gibbs, Bernhard F, Fasler-Kan, Elizaveta, Sumbayev, Vadim V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815087/
https://www.ncbi.nlm.nih.gov/pubmed/36599470
http://dx.doi.org/10.1136/jitc-2022-005714