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Copper coordination modulates prion conversion and infectivity in mammalian prion proteins
In mammals the cellular form of the prion protein (PrP(C)) is a ubiquitous protein involved in many relevant functions in the central nervous system. In addition to its physiological functions PrP(C) plays a central role in a group of invariably fatal neurodegenerative disorders collectively called...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815218/ https://www.ncbi.nlm.nih.gov/pubmed/36597284 http://dx.doi.org/10.1080/19336896.2022.2163835 |