Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury

Recently, we discovered that the cytokine interleukin-6 (IL-6) acts as a pituitary stem cell-activating factor, both when administered in vivo and when added to stem cell organoid cultures in vitro. Moreover, its expression, predominantly localized in the gland’s stem and mesenchymal cells, promptly...

Descripción completa

Detalles Bibliográficos
Autores principales: Laporte, Emma, De Vriendt, Silke, Hoekx, Julie, Vankelecom, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815540/
https://www.ncbi.nlm.nih.gov/pubmed/36619565
http://dx.doi.org/10.3389/fendo.2022.1092063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815540/
https://www.ncbi.nlm.nih.gov/pubmed/36619565
http://dx.doi.org/10.3389/fendo.2022.1092063

Ejemplares similares