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Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury
Recently, we discovered that the cytokine interleukin-6 (IL-6) acts as a pituitary stem cell-activating factor, both when administered in vivo and when added to stem cell organoid cultures in vitro. Moreover, its expression, predominantly localized in the gland’s stem and mesenchymal cells, promptly...
Autores principales: | Laporte, Emma, De Vriendt, Silke, Hoekx, Julie, Vankelecom, Hugo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815540/ https://www.ncbi.nlm.nih.gov/pubmed/36619565 http://dx.doi.org/10.3389/fendo.2022.1092063 |
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