A dsRNA-binding mutant reveals only a minor role of exonuclease activity in interferon antagonism by the arenavirus nucleoprotein

The arenavirus nucleoprotein (NP) plays an important role in the virus’ ability to block interferon (IFN) production, and its exonuclease function appears to contribute to this activity. However, efforts to analyze this contribution are complicated by the functional overlap between the exonuclease a...

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Detalles Bibliográficos
Autores principales: Bohn, Patrick, Waßmann, Irke, Wendt, Lisa, Leske, Anne, Hoenen, Thomas, Tews, Birke A., Groseth, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815661/
https://www.ncbi.nlm.nih.gov/pubmed/36603036
http://dx.doi.org/10.1371/journal.ppat.1011049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815661/
https://www.ncbi.nlm.nih.gov/pubmed/36603036
http://dx.doi.org/10.1371/journal.ppat.1011049

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