Orexin-A exerts neuroprotective effect in experimental intracerebral hemorrhage by suppressing autophagy via OXR1-mediated ERK/mTOR signaling pathway

BACKGROUND: Orexin-A (OXA) is a polypeptide produced in the hypothalamus, which binds to specific receptors and exerts multiple physiological effects. Autophagy plays a vital role in early brain injury (EBI) after intracerebral hemorrhage (ICH). However, the relationship between OXA and autophagy af...

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Detalles Bibliográficos
Autores principales: Zhang, Dexin, Cui, Ying, Zhao, Manman, Zheng, Xuecheng, Li, Chunyan, Wei, Jingbo, Wang, Kaijie, Cui, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815810/
https://www.ncbi.nlm.nih.gov/pubmed/36619670
http://dx.doi.org/10.3389/fncel.2022.1045034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815810/
https://www.ncbi.nlm.nih.gov/pubmed/36619670
http://dx.doi.org/10.3389/fncel.2022.1045034

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