Knockout of transient receptor potential ankyrin 1 (TRPA1) modulates the glial phenotype and alleviates perihematomal neuroinflammation after intracerebral hemorrhage in mice via MAPK/NF-κB signaling

The objective is to explore the role of astrocytic transient receptor potential ankyrin 1 (TRPA1) in glial phenotype transformation in neuroinflammation after intracerebral hemorrhage (ICH). Wild-type astrocytes and TRPA1(−/−) astrocytes were subjected to 6-h hemin treatment, and the calcium ions an...

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Detalles Bibliográficos
Autores principales: Xia, Min, Chen, Yù-Jié, Chen, Beike, Ru, Xufang, Wang, Jie, Lin, Jie, Tang, Xiaoqin, Chen, Weixiang, Hu, Rong, Li, Weina, Feng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Cellular, Molecular and Developmental Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815814/
https://www.ncbi.nlm.nih.gov/pubmed/36608163
http://dx.doi.org/10.1097/WNR.0000000000001862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9815814/
https://www.ncbi.nlm.nih.gov/pubmed/36608163
http://dx.doi.org/10.1097/WNR.0000000000001862

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