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CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1

Metastasis is an important factor contributing to poor prognosis in patients with gastric cancer; yet, the molecular mechanism leading to this cell behavior is still not well understood. In this study, we explored the role of cysteine protease inhibitor SN (Cystatin SN, CST1) in promoting gastric ca...

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Detalles Bibliográficos
Autores principales: Li, Dongbao, Wang, Yuhong, Dong, Chao, Chen, Tao, Dong, Anqi, Ren, Jiayu, Li, Weikang, Shu, Gege, Yang, Jiaoyang, Shen, Wenhao, Qin, Lei, Hu, Lin, Zhou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816059/
https://www.ncbi.nlm.nih.gov/pubmed/36369321
http://dx.doi.org/10.1038/s41388-022-02537-x