Adaptive activation of EFNB2/EPHB4 axis promotes post-metastatic growth of colorectal cancer liver metastases by LDLR-mediated cholesterol uptake

The microenvironment of distant organ plays vital roles in regulating tumor metastases. However, little is known about the crosstalk between metastasized tumor cells and target organs. Herein, we found that EFNB2 expression was upregulated in liver metastases (LM) of colorectal cancer (CRC), but not...

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Detalles Bibliográficos
Autores principales: Xu, Chunjie, Gu, Lei, Kuerbanjiang, Manzila, Jiang, Chunhui, Hu, Lipeng, Liu, Ye, Xue, Hanbing, Li, Jun, Zhang, Zhigang, Xu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816060/
https://www.ncbi.nlm.nih.gov/pubmed/36376513
http://dx.doi.org/10.1038/s41388-022-02519-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816060/
https://www.ncbi.nlm.nih.gov/pubmed/36376513
http://dx.doi.org/10.1038/s41388-022-02519-z

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