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Glycemia and β-cell function before and after elexacaftor/tezacaftor/ivacaftor in youth and adults with cystic fibrosis

BACKGROUND: Diabetes is prevalent among people with CF (PwCF) and associated with worse clinical outcomes. CFTR modulators are highly effective in improving the disease course of CF. However, the effects of elexacaftor/tezacaftor/ivacaftor (ETI) on glucose metabolism in PwCF are unclear. METHODS: Tw...

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Detalles Bibliográficos
Autores principales: Chan, Christine L., Granados, Andrea, Moheet, Amir, Singh, Sachinkumar, Vigers, Timothy, Arbeláez, Ana Maria, Yi, Yaling, Hu, Shanming, Norris, Andrew W., Ode, Katie Larson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816065/
https://www.ncbi.nlm.nih.gov/pubmed/36620757
http://dx.doi.org/10.1016/j.jcte.2022.100311