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The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

AIMS: To investigate the influence of the dose in the FITC-Dextran 4kDa (FD-4) permeability test in an obese mouse model, we tested the bodyweight dose regimen and a lean body mass-based dose regimen in high fat diet (HFD) mice and low fat diet (LFD) mice. We hypothesized that the FD-4 permeation re...

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Detalles Bibliográficos
Autores principales: Voetmann, Louise M., Rolin, Bidda, Kirk, Rikke K., Pyke, Charles, Hansen, Axel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816099/
https://www.ncbi.nlm.nih.gov/pubmed/36604407
http://dx.doi.org/10.1038/s41387-022-00230-2