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Spectrin-beta 2 facilitates the selective accumulation of GABA(A) receptors at somatodendritic synapses

Fast synaptic inhibition is dependent on targeting specific GABA(A)R subtypes to dendritic and axon initial segment (AIS) synapses. Synaptic GABA(A)Rs are typically assembled from α1-3, β and γ subunits. Here, we isolate distinct GABA(A)Rs from the brain and interrogate their composition using quant...

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Detalles Bibliográficos
Autores principales: Smalley, Joshua L., Cho, Noell, Ng, Shu Fun Josephine, Choi, Catherine, Lemons, Abigail H. S., Chaudry, Saad, Bope, Christopher E., Dengler, Jake S., Zhang, Chuansheng, Rasband, Matthew N., Davies, Paul A., Moss, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816108/
https://www.ncbi.nlm.nih.gov/pubmed/36604600
http://dx.doi.org/10.1038/s42003-022-04381-x