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Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression
Histone deacetylase (HDAC) is a kind of protease that modifies histone to regulate gene expression, and is usually abnormally activated in tumors. The approved pan-HDAC inhibitors have demonstrated clinical benefits for patients in some hematologic malignancies. Only limited therapeutic success in b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816171/ https://www.ncbi.nlm.nih.gov/pubmed/36604412 http://dx.doi.org/10.1038/s41392-022-01221-6 |