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Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression

Histone deacetylase (HDAC) is a kind of protease that modifies histone to regulate gene expression, and is usually abnormally activated in tumors. The approved pan-HDAC inhibitors have demonstrated clinical benefits for patients in some hematologic malignancies. Only limited therapeutic success in b...

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Detalles Bibliográficos
Autores principales: Hu, Zonglong, Wei, Fan, Su, Yi, Wang, Yafang, Shen, Yanyan, Fang, Yanfen, Ding, Jian, Chen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816171/
https://www.ncbi.nlm.nih.gov/pubmed/36604412
http://dx.doi.org/10.1038/s41392-022-01221-6