Individual radiosensitivity reflected by γ-H2AX and 53BP1 foci predicts outcome in PSMA-targeted radioligand therapy

PURPOSE: γ-H2AX and 53BP1 are fundamental for cellular DNA damage response (DDR) after radiation exposure and are linked to cell repair, arrest, or apoptosis. We aimed to evaluate whether DDR-markers in peripheral blood lymphocytes (PBLs) may have predictive potential for outcome in metastatic castr...

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Detalles Bibliográficos
Autores principales: Widjaja, Liam, Werner, Rudolf A., Krischke, Elke, Christiansen, Hans, Bengel, Frank M., Bogdanova, Natalia, Derlin, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816192/
https://www.ncbi.nlm.nih.gov/pubmed/36136101
http://dx.doi.org/10.1007/s00259-022-05974-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816192/
https://www.ncbi.nlm.nih.gov/pubmed/36136101
http://dx.doi.org/10.1007/s00259-022-05974-8

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