Genotoxicity of pyrrolizidine alkaloids in metabolically inactive human cervical cancer HeLa cells co-cultured with human hepatoma HepG2 cells

Pyrrolizidine alkaloids (PAs) are secondary plant metabolites, which can be found as contaminant in various foods and herbal products. Several PAs can cause hepatotoxicity and liver cancer via damaging hepatic sinusoidal endothelial cells (HSECs) after hepatic metabolization. HSECs themselves do not...

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Detalles Bibliográficos
Autores principales: Hadi, Naji Said Aboud, Bankoglu, Ezgi Eyluel, Stopper, Helga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Genotoxicity and Carcinogenicity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816206/
https://www.ncbi.nlm.nih.gov/pubmed/36273350
http://dx.doi.org/10.1007/s00204-022-03394-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816206/
https://www.ncbi.nlm.nih.gov/pubmed/36273350
http://dx.doi.org/10.1007/s00204-022-03394-z

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