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Human biodistribution and radiation dosimetry of the demyelination tracer [(18)F]3F4AP

PURPOSE: [(18)F]3F4AP is a novel PET radiotracer that targets voltage-gated potassium (K(+)) channels and has shown promise for imaging demyelinated lesions in animal models of neurological diseases. This study aimed to evaluate the biodistribution, safety, and radiation dosimetry of [(18)F]3F4AP in...

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Detalles Bibliográficos
Autores principales: Brugarolas, Pedro, Wilks, Moses Q., Noel, Jacqueline, Kaiser, Julia-Ann, Vesper, Danielle R., Ramos-Torres, Karla M., Guehl, Nicolas J., Macdonald-Soccorso, Marina T., Sun, Yang, Rice, Peter A., Yokell, Daniel L., Lim, Ruth, Normandin, Marc D., El Fakhri, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816249/
https://www.ncbi.nlm.nih.gov/pubmed/36197499
http://dx.doi.org/10.1007/s00259-022-05980-w