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Changes in stiffness of the extracellular and pericellular matrix in the anulus fibrosus of lumbar intervertebral discs over the course of degeneration

Analogous to articular cartilage, changes in spatial chondrocyte organisation have been proposed to be a strong indicator for local tissue degeneration in the intervertebral disc (IVD). While a progressive structural and functional degradation of the extracellular (ECM) and pericellular (PCM) matrix...

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Detalles Bibliográficos
Autores principales: Höflsauer, Sebastian, Bonnaire, Florian Christof, Bamberger, Charlotte Emma, Danalache, Marina, Feierabend, Martina, Hofmann, Ulf Krister
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816436/
https://www.ncbi.nlm.nih.gov/pubmed/36619385
http://dx.doi.org/10.3389/fbioe.2022.1006615