Genetically proxied inhibition of tumor necrosis factor and the risk of colorectal cancer: A drug-target mendelian randomization study

Background: Previous studies suggested that anti-TNF drugs might be repurposed as a preventive treatment for colorectal cancer. We aimed to examine whether genetically proxied inhibition of tumor necrosis factor receptor 1 (TNFR1) reduces the absolute risk of colorectal cancer through mendelian rand...

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Detalles Bibliográficos
Autores principales: Chen, Min, Chen, Qian, Xiao, Xin-Yu, Feng, Si-Jia, Wang, Xiao-Ying, Tang, Tai-Chun, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816472/
https://www.ncbi.nlm.nih.gov/pubmed/36618924
http://dx.doi.org/10.3389/fphar.2022.1079953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816472/
https://www.ncbi.nlm.nih.gov/pubmed/36618924
http://dx.doi.org/10.3389/fphar.2022.1079953

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