Inhibition of miR-146a-5p and miR-8114 in Insulin-Secreting Cells Contributes to the Protection of Melatonin against Stearic Acid-Induced Cellular Senescence by Targeting Mafa

BACKGROUND: Chronic exposure to elevated levels of saturated fatty acids results in pancreatic β-cell senescence. However, targets and effective agents for preventing stearic acid-induced β-cell senescence are still lacking. Although melatonin administration can protect β-cells against lipotoxicity...

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Detalles Bibliográficos
Autores principales: Su, Shenghan, Zhao, Qingrui, Dan, Lingfeng, Lin, Yuqing, Li, Xuebei, Zhang, Yunjin, Yang, Chunxiao, Dong, Yimeng, Li, Xiaohan, Regazzi, Romano, Sun, Changhao, Chu, Xia, Lu, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816504/
https://www.ncbi.nlm.nih.gov/pubmed/36475359
http://dx.doi.org/10.3803/EnM.2022.1565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816504/
https://www.ncbi.nlm.nih.gov/pubmed/36475359
http://dx.doi.org/10.3803/EnM.2022.1565

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