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Protein biosynthesis at the ER: finding the right accessories

More than 30% of eukaryotic proteins contain domains that must translocate across or integrate into the endoplasmic reticulum (ER) membrane. With few exceptions, protein translocation and transmembrane domain integration at the ER require the conserved Sec61 translocon. Decades of studies have estab...

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Detalles Bibliográficos
Autor principal: Shao, Sichen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816642/
https://www.ncbi.nlm.nih.gov/pubmed/36520029
http://dx.doi.org/10.1091/mbc.E21-09-0451