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Set1 regulates telomere function via H3K4 methylation–dependent and -independent pathways and calibrates the abundance of telomere maintenance factors

Set1 is an H3K4 methyltransferase that comprises the catalytic subunit of the COMPASS complex and has been implicated in transcription, DNA repair, cell cycle control, and numerous other genomic functions. Set1 also promotes proper telomere maintenance, as cells lacking Set1 have short telomeres and...

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Detalles Bibliográficos
Autores principales: Jezek, Meagan, Sun, Winny, Negesse, Maraki Y., Smith, Zachary M., Orosz, Alexander, Green, Erin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816643/
https://www.ncbi.nlm.nih.gov/pubmed/36416860
http://dx.doi.org/10.1091/mbc.E22-06-0213