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Set1 regulates telomere function via H3K4 methylation–dependent and -independent pathways and calibrates the abundance of telomere maintenance factors
Set1 is an H3K4 methyltransferase that comprises the catalytic subunit of the COMPASS complex and has been implicated in transcription, DNA repair, cell cycle control, and numerous other genomic functions. Set1 also promotes proper telomere maintenance, as cells lacking Set1 have short telomeres and...
Autores principales: | Jezek, Meagan, Sun, Winny, Negesse, Maraki Y., Smith, Zachary M., Orosz, Alexander, Green, Erin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816643/ https://www.ncbi.nlm.nih.gov/pubmed/36416860 http://dx.doi.org/10.1091/mbc.E22-06-0213 |
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