Aurora A phosphorylates Ndel1 to reduce the levels of Mad1 and NuMA at spindle poles

Dynein inactivates the spindle assembly checkpoint (SAC) by transporting checkpoint proteins away from kinetochores toward spindle poles in a process known as “stripping.” We find that inhibition of Aurora A kinase, which is localized to spindle poles, enables the accumulation of the spindle checkpo...

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Detalles Bibliográficos
Autores principales: Janczyk, Paweł Ł., Żyłkiewicz, Eliza, De Hoyos, Henry, West, Thomas, Matson, Daniel R., Choi, Won-Chan, Young, Heather M. Raimer, Derewenda, Zygmunt S., Stukenberg, P. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816647/
https://www.ncbi.nlm.nih.gov/pubmed/36350697
http://dx.doi.org/10.1091/mbc.E21-09-0438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816647/
https://www.ncbi.nlm.nih.gov/pubmed/36350697
http://dx.doi.org/10.1091/mbc.E21-09-0438

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