Cargando…

Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms

Embryonic morphogenesis is powered by dramatic changes in cell shape and arrangement driven by the cytoskeleton and its connections to adherens junctions. This requires robust linkage allowing morphogenesis without disrupting tissue integrity. The small GTPase Rap1 is a key regulator of cell adhesio...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez-Vale, Kia Z., Yow, Kristi D., Gurley, Noah J., Greene, Melissa, Peifer, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816648/
https://www.ncbi.nlm.nih.gov/pubmed/36287827
http://dx.doi.org/10.1091/mbc.E22-05-0176