Cargando…
Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms
Embryonic morphogenesis is powered by dramatic changes in cell shape and arrangement driven by the cytoskeleton and its connections to adherens junctions. This requires robust linkage allowing morphogenesis without disrupting tissue integrity. The small GTPase Rap1 is a key regulator of cell adhesio...
Autores principales: | Perez-Vale, Kia Z., Yow, Kristi D., Gurley, Noah J., Greene, Melissa, Peifer, Mark |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816648/ https://www.ncbi.nlm.nih.gov/pubmed/36287827 http://dx.doi.org/10.1091/mbc.E22-05-0176 |
Ejemplares similares
-
The Dilute domain of Canoe is not essential for Canoe’s role in linking adherens junctions to the cytoskeleton but contributes to robustness of morphogenesis
por: McParland, Emily D., et al.
Publicado: (2023) -
Exploring the evolution and function of Canoe’s intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis
por: Gurley, Noah J., et al.
Publicado: (2023) -
Exploring the evolution and function of Canoe’s intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis
por: Gurley, Noah J., et al.
Publicado: (2023) -
Rap1 and Canoe/afadin are essential for establishment of apical–basal polarity in the Drosophila embryo
por: Choi, Wangsun, et al.
Publicado: (2013) -
The single Drosophila ZO-1 protein Polychaetoid regulates embryonic morphogenesis in coordination with Canoe/afadin and Enabled
por: Choi, Wangsun, et al.
Publicado: (2011)