Loss-of-function approach using mouse retinal explants showed pivotal roles of Nmnat2 in early and middle stages of retinal development

Nicotinamide mononucleotide adenylyltransferase (Nmnat) is a class of enzymes with three members (Nmnat1–3). Nmnat1 is in nucleus and associated with Leber congenital amaurosis, a form of early-onset retinal degeneration, while Nmnat2 is in cytoplasm and a well-characterized neuroprotective factor....

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Detalles Bibliográficos
Autores principales: Kuribayashi, Hiroshi, Katahira, Miku, Aihara, Makoto, Suzuki, Yutaka, Watanabe, Sumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816650/
https://www.ncbi.nlm.nih.gov/pubmed/36322391
http://dx.doi.org/10.1091/mbc.E22-03-0078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816650/
https://www.ncbi.nlm.nih.gov/pubmed/36322391
http://dx.doi.org/10.1091/mbc.E22-03-0078

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