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Research of storable and ready-to-use artificial red blood cells (hemoglobin vesicles) for emergency medicine and other clinical applications

Hemoglobin (Hb) is the most abundant protein in blood, with concentration of about 12–15 g/dl. The highly concentrated Hb solution (35 g/dl) is compartmentalized in red blood cells (RBCs). Once Hb is released from RBCs by hemolysis during blood circulation, it induces renal and cardiovascular toxici...

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Detalles Bibliográficos
Autores principales: Sakai, Hiromi, Kure, Tomoko, Taguchi, Kazuaki, Azuma, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816666/
https://www.ncbi.nlm.nih.gov/pubmed/36619343
http://dx.doi.org/10.3389/fmedt.2022.1048951