One-step generation of a conditional allele in mice using a short artificial intron

Despite tremendous advances in genome editing technologies, generation of conditional alleles in mice has remained challenging. Recent studies in cells have successfully made use of short artificial introns to engineer conditional alleles. The approach consists of inserting a small cassette within a...

Descripción completa

Detalles Bibliográficos
Autores principales: Cassidy, Annelise M., Thomas, Destinée B., Kuliyev, Emin, Chen, Hanying, Pelletier, Stephane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816766/
https://www.ncbi.nlm.nih.gov/pubmed/36619446
http://dx.doi.org/10.1016/j.heliyon.2022.e12630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816766/
https://www.ncbi.nlm.nih.gov/pubmed/36619446
http://dx.doi.org/10.1016/j.heliyon.2022.e12630

Ejemplares similares