eNAMPT/TLR4 inflammatory cascade activation is a key contributor to SLE Lung vasculitis and alveolar hemorrhage

RATIONALE: Effective therapies to reduce the severity and high mortality of pulmonary vasculitis and diffuse alveolar hemorrhage (DAH) in patients with systemic lupus erythematosus (SLE) is a serious unmet need. We explored whether biologic neutralization of eNAMPT (extracellular nicotinamide phosph...

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Detalles Bibliográficos
Autores principales: Tumurkhuu, Gantsetseg, Casanova, Nancy G., Kempf, Carrie L., Ercan Laguna, Duygu, Camp, Sara M., Dagvadorj, Jargalsaikhan, Song, Jin H., Reyes Hernon, Vivian, Travelli, Cristina, Montano, Erica N., Yu, Jeong Min, Ishimori, Mariko, Wallace, Daniel J., Sammani, Saad, Jefferies, Caroline, Garcia, Joe G.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816774/
https://www.ncbi.nlm.nih.gov/pubmed/36619655
http://dx.doi.org/10.1016/j.jtauto.2022.100181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816774/
https://www.ncbi.nlm.nih.gov/pubmed/36619655
http://dx.doi.org/10.1016/j.jtauto.2022.100181

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