Epigenetic regulator KDM4A activates Notch1-NICD-dependent signaling to drive tumorigenesis and metastasis in breast cancer

BACKGROUND: Altered epigenetic reprogramming and events contribute to breast cancer (Bca) progression and metastasis. How the epigenetic histone demethylases modulate breast cancer progression remains poorly defined. We aimed to elucidate the biological roles of KDM4A in driving Notch1 activation an...

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Detalles Bibliográficos
Autores principales: Pei, Jing, Zhang, ShengQuan, Yang, Xiaowei, Han, Chunguang, Pan, Yubo, Li, Jun, Wang, Zhaorui, Sun, Chenyu, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816809/
https://www.ncbi.nlm.nih.gov/pubmed/36592610
http://dx.doi.org/10.1016/j.tranon.2022.101615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816809/
https://www.ncbi.nlm.nih.gov/pubmed/36592610
http://dx.doi.org/10.1016/j.tranon.2022.101615

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