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Targeting chromosome 12q amplification in relapsed glioblastoma: the use of computational biological modeling to identify effective therapy—a case report

BACKGROUND: Relapsed glioblastoma (GBM) is often an imminently fatal condition with limited therapeutic options. Computation biological modeling, i.e., biosimulation, of comprehensive genomic information affords the opportunity to create a disease avatar that can be interrogated in silico with vario...

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Detalles Bibliográficos
Autores principales: Castro, Michael P., Khanlou, Negar, Fallah, Aria, Pampana, Anusha, Alam, Aftab, Lala, Deepak Anil, Roy, Kunal Ghosh Ghosh, Amara, Anish Raju R., Prakash, Annapoorna, Singh, Divya, Behura, Liptimayee, Kumar, Ansu, Kapoor, Shweta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816820/
https://www.ncbi.nlm.nih.gov/pubmed/36618786
http://dx.doi.org/10.21037/atm-2022-62