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Targeting chromosome 12q amplification in relapsed glioblastoma: the use of computational biological modeling to identify effective therapy—a case report
BACKGROUND: Relapsed glioblastoma (GBM) is often an imminently fatal condition with limited therapeutic options. Computation biological modeling, i.e., biosimulation, of comprehensive genomic information affords the opportunity to create a disease avatar that can be interrogated in silico with vario...
Autores principales: | Castro, Michael P., Khanlou, Negar, Fallah, Aria, Pampana, Anusha, Alam, Aftab, Lala, Deepak Anil, Roy, Kunal Ghosh Ghosh, Amara, Anish Raju R., Prakash, Annapoorna, Singh, Divya, Behura, Liptimayee, Kumar, Ansu, Kapoor, Shweta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816820/ https://www.ncbi.nlm.nih.gov/pubmed/36618786 http://dx.doi.org/10.21037/atm-2022-62 |
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