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Raltitrexed as a substitute for capecitabine in metastatic gastric cancer: a case report and literature review

BACKGROUND: 5-Fluorouracil and its oral prodrug, capecitabine, are frequently used in the treatment of gastrointestinal cancers—including gastric cancer—but carry a cardiotoxicity risk. Raltitrexed (brand name Tomudex), a direct inhibitor of thymidylate synthase, has been successfully used as an alt...

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Detalles Bibliográficos
Autores principales: Ladak, Imran, Preti, Beatrice, Dias, Bryan, Breadner, Daniel Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9816848/
https://www.ncbi.nlm.nih.gov/pubmed/36618781
http://dx.doi.org/10.21037/atm-2022-69