Frequent somatic mosaicism in T lymphocyte subsets in individuals with and without multiple sclerosis

BACKGROUND: Somatic variants are variations in an individual’s genome acquired after the zygotic stadium and result from mitotic errors or not (fully) repaired DNA damage. OBJECTIVES: To investigate whether somatic mosaicism in T lymphocyte subsets is enriched early in multiple sclerosis (MS). METHO...

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Detalles Bibliográficos
Autores principales: Van Horebeek, Lies, Dedoncker, Nina, Dubois, Bénédicte, Goris, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817019/
https://www.ncbi.nlm.nih.gov/pubmed/36618380
http://dx.doi.org/10.3389/fimmu.2022.993178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817019/
https://www.ncbi.nlm.nih.gov/pubmed/36618380
http://dx.doi.org/10.3389/fimmu.2022.993178

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