Cargando…

Frequent somatic mosaicism in T lymphocyte subsets in individuals with and without multiple sclerosis

BACKGROUND: Somatic variants are variations in an individual’s genome acquired after the zygotic stadium and result from mitotic errors or not (fully) repaired DNA damage. OBJECTIVES: To investigate whether somatic mosaicism in T lymphocyte subsets is enriched early in multiple sclerosis (MS). METHO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Van Horebeek, Lies, Dedoncker, Nina, Dubois, Bénédicte, Goris, An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817019/ https://www.ncbi.nlm.nih.gov/pubmed/36618380 http://dx.doi.org/10.3389/fimmu.2022.993178

Ejemplares similares

A targeted sequencing extension for transcript genotyping in single-cell transcriptomics
por: Van Horebeek, Lies, et al.
Publicado: (2023)

CHIT1 at Diagnosis Reflects Long‐Term Multiple Sclerosis Disease Activity
por: Oldoni, Emanuela, et al.
Publicado: (2020)

Body Mass Index, Interleukin-6 Signaling and Multiple Sclerosis: A Mendelian Randomization Study
por: Vandebergh, Marijne, et al.
Publicado: (2022)

A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease
por: Van Horebeek, Lies, et al.
Publicado: (2019)

Progress in Multiple Sclerosis Genetics
por: Goris, An, et al.
Publicado: (2012)

Treatment-Induced BAFF Expression and B Cell Biology in Multiple Sclerosis
por: Smets, Ide, et al.
Publicado: (2021)

Somatic recombination underlies frequent revertant mosaicism in loricrin keratoderma
por: Suzuki, Shotaro, et al.
Publicado: (2019)

Natural Killer Cells in Multiple Sclerosis: Entering the Stage
por: Beliën, Jarne, et al.
Publicado: (2022)

Effects of Vitamin D and Body Mass Index on Disease Risk and Relapse Hazard in Multiple Sclerosis: A Mendelian Randomization Study
por: Vandebergh, Marijne, et al.
Publicado: (2022)

Homeostasis of lymphocytes and monocytes in frequent blood donors
por: Ratts, Robert B., et al.
Publicado: (2012)

B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes
por: Egia-Mendikute, Leire, et al.
Publicado: (2019)

Immunological Subsets Characterization in Newly Diagnosed Relapsing–Remitting Multiple Sclerosis
por: D’Amico, Emanuele, et al.
Publicado: (2022)

Demonstration of Functional Heterogeneity of T lymphocytes and Identification of Their Two Major Subsets
por: Kisielow, Paweł
Publicado: (2014)

Quantitative MRI phenotypes capture biological heterogeneity in multiple sclerosis patients
por: Smets, Ide, et al.
Publicado: (2021)

Somatic Genomic Mosaicism in Multiple Myeloma
por: Ye, Christine J., et al.
Publicado: (2020)

Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target
por: Liu, Rongzeng, et al.
Publicado: (2022)

Frequent Somatic Mutation in Adult Intestinal Stem Cells Drives Neoplasia and Genetic Mosaicism during Aging
por: Siudeja, Katarzyna, et al.
Publicado: (2015)

The Choroid Plexus Is Permissive for a Preactivated Antigen-Experienced Memory B-Cell Subset in Multiple Sclerosis
por: Haas, Jürgen, et al.
Publicado: (2021)

Characterization of antigen-specific CD8+ memory T cell subsets in peripheral blood of patients with multiple sclerosis
por: Liu, Pen-Ju, et al.
Publicado: (2023)

Late-Onset Cryopyrin-Associated Periodic Syndromes Caused by Somatic NLRP3 Mosaicism—UK Single Center Experience
por: Rowczenio, Dorota M., et al.
Publicado: (2017)

Imbalance of Peripheral Lymphocyte Subsets in Patients With Ankylosing Spondylitis: A Meta-Analysis
por: Liu, Dong, et al.
Publicado: (2021)

Effect of dimethyl fumarate on lymphocyte subsets in patients with relapsing multiple sclerosis
por: Buckle, Guy, et al.
Publicado: (2020)

Possible Somatic Mosaicism of Novel FUS Variant in Familial Amyotrophic Lateral Sclerosis
por: Hisahara, Shin, et al.
Publicado: (2021)

Identification of Distinct Unmutated Chronic Lymphocytic Leukemia Subsets in Mice Based on Their T Cell Dependency
por: Pal Singh, Simar, et al.
Publicado: (2018)

Blood Lymphocyte Subsets for Early Identification of Non-Remission to TNF Inhibitors in Rheumatoid Arthritis
por: Rodríguez-Martín, Eulalia, et al.
Publicado: (2020)

Changes in T Lymphocyte Subsets in Different Tumors Before and After Radiotherapy: A Meta-analysis
por: Wang, Qin, et al.
Publicado: (2021)

Somatic Mosaicism in the Human Genome
por: Freed, Donald, et al.
Publicado: (2014)

Somatic mosaicism in the diseased brain
por: Iourov, Ivan Y., et al.
Publicado: (2022)

Nomogram based on circulating lymphocyte subsets for predicting radiation pneumonia in esophageal squamous cell carcinoma
por: Zhang, Xiao-zhen, et al.
Publicado: (2022)

Impact of Chronic HIV/SIV Infection on T Follicular Helper Cell Subsets and Germinal Center Homeostasis
por: Graff-Dubois, Stéphanie, et al.
Publicado: (2016)

Brain Antigens Stimulate Proliferation of T Lymphocytes With a Pathogenic Phenotype in Multiple Sclerosis Patients
por: Gottlieb, Assaf, et al.
Publicado: (2022)

Negative Clinical Evolution in COVID-19 Patients Is Frequently Accompanied With an Increased Proportion of Undifferentiated Th Cells and a Strong Underrepresentation of the Th1 Subset
por: Gutiérrez-Bautista, Juan Francisco, et al.
Publicado: (2020)

Individual Sea Urchin Coelomocytes Undergo Somatic Immune Gene Diversification
por: Oren, Matan, et al.
Publicado: (2019)

Absolute count of T and B lymphocyte subsets is decreased in systemic sclerosis
por: Gambichler, T, et al.
Publicado: (2010)

Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis
por: Fox, David A., et al.
Publicado: (2021)

Somatic mosaicism in plants with special reference to somatic crossing over
por: Vig, Baldev K.
Publicado: (1978)

Hypothesis: Somatic Mosaicism and Parkinson Disease
por: Kim, Han-Joon, et al.
Publicado: (2014)

Somatic Mosaicism and Autism Spectrum Disorder
por: D’Gama, Alissa M.
Publicado: (2021)

Somatic Mosaicism in Blaschkolinear Inflammatory Disorders
por: Theodosakis, Nicholas, et al.
Publicado: (2016)

Treatment effects of fingolimod in multiple sclerosis: Selective changes in peripheral blood lymphocyte subsets
por: Hjorth, Maria, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t6j43c6b5nh6a00o61hcupindh