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Osteopontin Promotes Macrophage M1 Polarization by Activation of the JAK1/STAT1/HMGB1 Signaling Pathway in Nonalcoholic Fatty Liver Disease

BACKGROUND AND AIMS: Osteopontin (OPN) is reported to be associated with the pathogenesis of nonalcoholic fatty liver disease (NAFLD). However, the function of OPN in NAFLD is still inconclusive. Therefore, our aim in this study was to evaluate the role of OPN in NAFLD and clarify the involved mecha...

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Detalles Bibliográficos
Autores principales: Xu, Zhihao, Xi, Feiyang, Deng, Xinxin, Ni, Yuqi, Pu, Changqin, Wang, Dan, Lou, Weiming, Zeng, Xufang, Su, Ning, Chen, Chen, Zeng, Ziqiang, Deng, Libin, Jiang, Meixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817049/
https://www.ncbi.nlm.nih.gov/pubmed/36643029
http://dx.doi.org/10.14218/JCTH.2021.00474