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Reduction in Intrahepatic cccDNA and Integration of HBV in Chronic Hepatitis B Patients with a Functional Cure

BACKGROUND AND AIMS: Functional cure (FC) is characterized by the clearance of the hepatitis B surface antigen from the serum of patients with chronic hepatitis B (CHB). However, the level of intrahepatic covalently closed circular DNA (cccDNA) and hepatitis B virus (HBV) integration remains unclear...

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Detalles Bibliográficos
Autores principales: Gan, Weiqiang, Gao, Na, Gu, Lin, Mo, Zhishuo, Pang, Xiuqing, Lei, Ziying, Gao, Zhiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817062/
https://www.ncbi.nlm.nih.gov/pubmed/36643049
http://dx.doi.org/10.14218/JCTH.2022.00177