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Nonclassical Crystallization and Core–Shell Structure Formation of Ibuprofen from Binary Solvent Solutions

[Image: see text] Liquid–liquidphase separation (LLPS) or dense liquid intermediates during the crystallization of pharmaceutical molecules is common; however, their role in alternative nucleation mechanisms is less understood. Herein, we report the formation of a dense liquid intermediate followed...

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Detalles Bibliográficos
Autores principales: Mani, Rajaboopathi, Peltonen, Leena, Strachan, Clare J., Karppinen, Maarit, Louhi-Kultanen, Marjatta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817074/
https://www.ncbi.nlm.nih.gov/pubmed/36624777
http://dx.doi.org/10.1021/acs.cgd.2c00971