Characterization of the Novel P2X7 Receptor Radioligand [(3)H]JNJ-64413739 in Human Brain Tissue

[Image: see text] Radioligands targeting microglia cells have been developed to identify and determine neuroinflammation in the living brain. One recently discovered ligand is JNJ-64413739 that binds selectively to the purinergic receptor P2X7R. The expression of P2X7R is increased under inflammatio...

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Detalles Bibliográficos
Autores principales: Mikkelsen, Jens D., Aripaka, Sanjay S., Kaad, Sif, Pazarlar, Burcu A., Pinborg, Lars, Finsen, Bente, Varrone, Andrea, Bang-Andersen, Benny, Bastlund, Jesper F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817075/
https://www.ncbi.nlm.nih.gov/pubmed/36535632
http://dx.doi.org/10.1021/acschemneuro.2c00561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817075/
https://www.ncbi.nlm.nih.gov/pubmed/36535632
http://dx.doi.org/10.1021/acschemneuro.2c00561

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