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Impact of m6A demethylase (ALKBH5, FTO) genetic polymorphism and expression levels on the development of pulmonary tuberculosis

OBJECTIVE: The m6A methylation was involved in the pathogenesis of pulmonary tuberculosis (PTB), and our study aimed to reveal the potential association of m6A demethylase (ALKBH5, FTO) genes variation, expression levels and PTB. METHODS: Eight SNPs (ALKBH5 gene rs8400, rs9913266, rs12936694, rs4925...

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Detalles Bibliográficos
Autores principales: Zhang, Tian-Ping, Li, Rui, Wang, Li-Jun, Li, Hong-Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9817133/
https://www.ncbi.nlm.nih.gov/pubmed/36619747
http://dx.doi.org/10.3389/fcimb.2022.1074380